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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9d0921faa34280e003732fee26f8e03de1b5e29923118f93cf2ce450e18b388' 
  AND token = 'qBXQEaefwKvNDIqG1YoHpvxEVZp9jmcg0jqhY+4Qnpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}