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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8875caf58d1b7c3f67785df934fe9c6b680a258243113b8bf0a243d419c7b2a' 
  AND token = 'wqedA556GlzaaCQrnRi01wSZ9jEOkIXB3XRotfNAp7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}