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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34606e05f206f5449083dc2608272809ed013bed23f975207bff7eaa8605c755' 
  AND token = 'U/KwfH2sWvBnEFUgYEoUw+Z/t+Qr8+axevUl7I0D3lM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}