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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2803b674e80ccc23f34d1ab493f4db8c7c1467ddf7ef01ea79b6e1ededc57289' 
  AND token = 'NAt3qO5Y1WXmFtT2BeX7skd1sdFd64IIaTl0q/XJl1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}