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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6468d9399ddca8636d08ad563f40bea88938a6689c8a0262480a2dc6bd921975' 
  AND token = 'tkve8A42t87OlyqNZ6+JwRW7q2KG+zJFaNYqrLoSYS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}