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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c225dd31cac0ab3324907b7ecdcc7738123745ff0f7112a60ba5780e3a9d5aa' 
  AND token = '3Ng77f9WsGkyDdyJZ9+OK+Ck3Cd6a+A1b4ydUR0baGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}