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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57977e0dda8af8d76eb9a4d733fc0f243b4b042ecfcd05e48b642c157f52bdb6' 
  AND token = 'XZGqeJSuISUDR2Uo4L+2YiEPlJKERlKgL1UL38aaKxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}