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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4c49d48bb803534a1e158fdcd4d797e8f1f26ae2b4321ed6c25d0e086d8ec54' 
  AND token = 'pb67RDKTBUV7ou6BCi1opVIFkcYHFMSfNHoi4xyEX3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}