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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd53e8355804d35398a03d555e4bc0423a8651879b8c5c728e2467749a1c55479' 
  AND token = 'Lu/t2HmGjizVxp51EOirytIUw0F1HnMd71v1OxMYrjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}