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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ef8f20f7a19dafae6e540c253e511bf3e3bdd5009ca3a48997b5624d2974815' 
  AND token = 'yLhcq/FdVrO9FrBL8JLX9La92pEXyWcz9p7XIA6OvjQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00078

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}