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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3666676234451921d7ead8a1ca0b5005695a2434c12adc8ad9f479c9e70ff493' 
  AND token = 'JqLs1rzM5rLhWEe7uW2XsnTAp0ZZqo/aS/Jvqu/MWJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}