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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '759978db88a6b155d2cedb07255bedb879db16bc655129ad113d9573f7198bf9' 
  AND token = 'OsDxsm81YT8f++dnQnYCx1M3H0QY8b1DHlQhk5Qvl54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}