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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '225d64c7af27251eced6c36e3bf90cca73b9352ad1ccb6b08e3f5037ce71cc46' 
  AND token = 'KPKFwifa9ejqaPR5ksZrgrLPS/beg/LWWkL4/BCPwRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}