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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ac030a9c23f185382e771f9a7e354678bdfb36e660d252be8218e5236ede697' 
  AND token = '78IIBbG4NGGaiD4fmkBU9vHedkWano5F46uVWVTWt7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}