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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b59e0da32b35e6231f46bf7f47d6f1dcd9b7599a6c8b80dc405c27090b44b012' 
  AND token = 'Q3gCLoMR6d4p1K6A0z1O9ixiNbcIUOxDIqAIRUq8fmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}