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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e2a9911de09d72ff8ccb2ceaaa1f65014fad22e4670e0bccc56838734d7c221' 
  AND token = 'GmNitGr813YVKQnD06FpNR/ZI5dtoIYfOUM8uBDshck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}