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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1dbe961c62a61773307cc3d4f769c112b5ee42c2db7c7680658fa5da6c99d22' 
  AND token = 's2fYJtHQnu7nvv/wKCzKna1W3Fd4VLiL5/KfaqdHtZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}