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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29bd2d322aa2932ef749b2866fcc0610e1d93643258ddac223f56654754f18c0' 
  AND token = 'RvNrEcxAyOrp/j4pRyRimhFT7gMzfpuxcOeR8fL++qM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}