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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2cf7c7aeebd693194b654c1f47e35e8a7e98ac151553324545aa780c6f74eeb' 
  AND token = 'w/P2SLLExh5cbG1i3P9BoTJFbHUjiTRWgJTFL2pUGng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}