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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4eb25ce729b7856e3017ef67b2b9d2c1e4208ab5e21a474a1f0c5a92c133d600' 
  AND token = 'bs6wnJPSOofhQ0wkHLmBC4v9/UdPYqtJ3Jgpv40ybns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}