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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c95d621b5442ad331671f6730a0ab4aa10a7dff25166c0f7be76f4c41c2f2edb' 
  AND token = 'cuVlQPayqnXTUEzwNyRDxZq0PQgZD+w61CE5Pxt67uM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}