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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0794c8e2fd393db9ab6ce5de6868d12618733f4ea3dc48d21515b5a527c21163' 
  AND token = 'ORJB+Ub4kwr3vngfXyn1gCgtntysRainQ+p+uPc5tdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}