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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9d345bb7ade7636173258f5b7de20cc9769f9913b0fc7778f9667c09a90bec0' 
  AND token = '/ZhmWfc8KwCJBR7mMeYasyzJdzFG7Ayp33S4q1iwKd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}