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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '672801db32a3dba8f0052cd947fe4706effd0457a2cd0f717b4401fc665a3def' 
  AND token = 'ctCnU44MZ/ef2VSXklYs4VPdBwBM7o6vGNujeHL3qbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}