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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '353a6f9dce9b8d5c3d10536845b733cb8ef8803d4fbaa919b56b3f17cd6e90e2' 
  AND token = '5GTpAH7SeT6Cfw+E6penAyHBDbqZmKLAhUT+zQgUsYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}