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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e21b8ab0c30f263f4b8b747e818871fbd4a3123f1526ae0d2855e852f01e78b6' 
  AND token = 'An0uET0Mz3Hm2VMShPg+d8DY1WjYGhb3+WNei7GmZT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}