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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad12462a50204ad2684b3a5c2a133485c79f587c930b4a52fdae63af71c52211' 
  AND token = 'uNAs6Xmpc242lsTrAGOGzzuTayr63zFN118MEADXyjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}