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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '461adbe83018e16cf5ec404635c080d0bfaddd18535a7cbee62e9b5d8d975f04' 
  AND token = '1filZKSVjX+u0xYXN5pTXnpVPRB6VdPPwDBEUHSOYpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}