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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7780d5658a7bbe6e89e69bfa2a69e33ad7dd1bca4c80318e4165f2c7ca5350fa' 
  AND token = '4Q0H5dlnmzLcB0sqziYLih+8IkBRaQyNnKYCvfWMXp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}