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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6c15ff87d0a5c4597ce9cee8f862858989be1005a615e618bc122d6d541e366' 
  AND token = 'SsAambMDE9G9TLU0AZqn+QlB1GQOhueHwDEiO+1/XpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}