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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e65b4d4dfc8b1811ca02cd0eb3e40d060d81cb180aaf2fa4e386b8816aed4e41' 
  AND token = 'IWq11fHdbpF7zkHALI0OYrtUo8IiOchAQ5s4oorappY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}