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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7ddc023d51954f9a453caad75a2d5c031fadc2147983067f561a56d5b4fa370' 
  AND token = '10Yrn2lnIJspFfnRIGXKOy2P+3A/J4GN3EjvD+wKjtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}