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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3adaf96ac05d555e44b0a6f8bde2a393b788136b0181eea4347d65bd2f49cab' 
  AND token = 'Q/Cd6rVJSKNH827WibJFxsJYK5KjflU7Ds+oJb07ZnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}