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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78b852a5da368c1852bff0aee6ca1b21c138b451d4acdb1762ebe7d84807cd81' 
  AND token = '2tfcPmyOAYI+5tTPGDkL6DnZh74KY1yn4WerYKrRISw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}