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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e397be0cfd03e47eb8e45d4e2446d0976d352dc482c4c90ef6314986c8d72f22' 
  AND token = 'z846F4pa4qCgSLqRbqQX9nrQX84MbKNWRF9Kom69CI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}