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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18bab67993e163006b902d1b837dbd7f597b9b2f6fb1ea44b826e20c8bdeb4be' 
  AND token = 'QSh2OOHQDFA2xKsmX5H0FUZ1L48btZlQhzTr6aSuXNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}