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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4147db552d26498d2d0baddf21c36b40875888d3d16ec669bde8093514cbe36' 
  AND token = 'FxX8iTWDF4XYwu5FmhmaCG8r6yeAUVy/qng2n87yxSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}