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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43b08ddb2477d27d45bac6d5b9220106e3d3c2e51ad29515b90be0070b8f4a34' 
  AND token = 'Hllr9+jg1jQGI4H6Skhi3qkVM5+JAcs6ExxLUaNAQPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}