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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fa6526a3499f2625f3bbf4202724dd22ffedd4bea6ccad11c78c6f058c2928e' 
  AND token = 'eGFIkj4aDO4TNBnxnRfyE5RigPbf1DqIhfVAgj4O7dE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}