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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce48f6cbe774f5676becf755aad8210e682563b9120c1d60d9a37036e0c55498' 
  AND token = 'jp6LUM7qJQcChkBfL6bvvBtYNiyV6KYr0WpqvSnmMew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}