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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfe9c84644c403822c1575f79a9d815a20a3dc17e811493dd4193f1d33521c8d' 
  AND token = 'JT2NFLXoLUkGZquC+5EyBFrXmIMcIWJ3b884G2yb+Xc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}