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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f9c1d5fc2efc90bc60dacc9fcc3b7e89871d14ea97e5a64d6c821b6603d2172' 
  AND token = 'If2p10NwzSMY7PuHvyd4YAfcOxTqEUnvyW+o6OeQqFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}