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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51fbbf817dedc50910ed7cdff81079305f8e83cc79c50499679bce87bd84f2ef' 
  AND token = 'CPcZTA1tQLvFB8YZxS+gYk8LsMmXx9giYESNrig2Ydg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}