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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23e4ffd01875ece2df2f0fc770607ee618dba726de100ad9fd9640cd4ee64f6e' 
  AND token = 'Xy9eacVj/DmCcq6hofD8IEOSsRRAWMoj8YtJk2ZULdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}