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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c78b533a77ebfbb9d1354d2701486d213e8d12d7eb0175f449d42ecb9b6b39e2' 
  AND token = 'QLJ1GAaAp3Eb3wAoABUbYmC5oyi4ml3jLvvkNPbdvFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}