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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b92d86db137263ed04f0d0ad171de2cf9b0b65a549dc1cd52728b2f2f20a76aa' 
  AND token = 'ScVyPdF6r8EnF5sTernDFnQioFb2snqTzRDZm/OapUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}