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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0dc4a05dbbbda8a61ba72caad142a4907dbdc51d4119c64c1ada539109d4035c' 
  AND token = 'Pfrc9gFeD7UpE/TZRjMZe4x/gHrINMiSz4sjLaG04ww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}