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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17603f51e1f298ba45b6137d5c5068c5104d16bf75fcd0d39db397de888cbad3' 
  AND token = '2qufrmEBGuJhrKvIZbi1zTQOcjt6+5hkL57NaH6uF84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}