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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78d5f94b44d5173a806d9ab6cdf01ed669430bcb54de68b3c72d5223efa8acf2' 
  AND token = 'lUrT2EJ8D9Ul3KbypO9+RCJAiCG+ZpGVF3KnPkRLFM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}