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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '269e0f499cc8c2ecf557baf452e2a07104bd84602ab80e1f03fedeee538c99c4' 
  AND token = 'EWDZN4uPHYya8Qgdbzwimca8f3NSUk4nXcy3rIAS5zg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}